The biological clock, the mechanism by which organisms control their daily rhythms, predict and prepare for future changes, regulates daily, monthly and seasonal changes in many chemical processes. Experts said that disruption of the circadian clock is known to be linked to the development of many diseases, such as cancer, diabetes, various metabolic and neurological diseases, and sleep disorders.
Scientists have made a remarkable assessment of the biological clock and its importance.
Experts defined the biological clock as “the mechanism by which organisms control their daily rhythms, predict and prepare for future changes.”
The biological clock regulates the changes of many chemical processes
Experts said the biological clock regulates the daily, monthly and seasonal changes of many chemical processes. Experts recommend daily rhythms, such as sleep; Rhythmic changes in behavior or physiology such as blood pressure, temperature, metabolic rates, annual rhythms such as preparing for migration by eating plenty of food, preparing for winter by hibernating by storing food, the fact that some creatures are in the most active form at dawn and dusk, and the blooming of flowers at certain times of the day are regulated by the organism’s internal clock, that is, the biological clock.
It provides a 24-hour layout…
Stating that the circadian clock has been defined in almost all organisms, from bacteria to humans, the scientists said, “The circadian clock provides a 24-hour pattern for processes at many levels, from gene expression to the behavior of the organism, and is an adaptation to the rotation of the earth.”
The circadian clock is divided into two
Stating that the circadian clock in humans is divided into two parts, the researchers said, “It is the central clock in the suprachiasmatic nucleus of the hypothalamus in the brain and the peripheral clocks found in almost every tissue and organ system.”
“The central clock accepts the input of light from the retina in the eye, this information is converted into a chemical version to change the levels of clock genes in specific neurons there, and to synchronize by transmitting to peripheral organs and cells in other brain parts,” the experts said.
The Nobel Prize brought…
Stating that the circadian molecular clock in the cells that make up the central and peripheral clocks consists of a cyclical mechanism formed by the activation and suppression of the master clock genes (Clock, Bmal1, Period 1-3 and Cryptocrome1-3), the researchers said, “This mechanism; gives daily rhythmitis to many biochemical and physiological functions. In 2017, the Nobel Prize in Physiology/Medicine was awarded to three scientists who discovered the molecular mechanisms that control the circadian rhythm in fruit flies. Nobel Prize-winning scientist Prof. Dr. Aziz Sancar is a scientist who has made a significant contribution to this field with his studies on the clock regulation mechanism of the Cryptocrome gene and the relationship of the clock with DNA repair and cancer.”
The biological clock allows some genes to be regulated
Noting that the dissynchronization between the external environment and the clock causes many problems, the doctors said, “One of them is jet-lag, which occurs because the internal clock of our body has difficulty adapting when we travel in more than one time zone. “The circadian clock has the role of regulating certain genes expressed in any cell.”
Disruption of the biological clock can lead to health problems
Medical experts say that it is known that the disruption of the circadian clock is linked to the development of many diseases such as cancer, diabetes, various metabolic and neurological diseases and sleep disorders, “In addition, in recent years, studies on how the circadian clock works and its relationship with many diseases have shown that the clock can be a personalized treatment tool.”